One mole is the amount of a substance that contains as many particles or entities as there are atoms in exactly 12 g of the isotope .
A mole of a substance always contains the same number of entities , no matter what the substance may be. In order to determine this number precisely , the mass of carbon -12 atom was determined by mass spectrometer and found to be equal to 1.992648 x 10-23 g. Knowing that one mole of carbon weighs 12 g . the number of atoms in it is equal to :
6.0221367 x 1023